Publikationen

(Auswahl)

Peters, T., Ziegler, M., Kinkl, N., & Zrenner, E. (2026). Sicherheit und Wirksamkeit einer beidseitigen, einmaligen subretinalen Injektion von rAAV. hCNGA3 in Erwachsenen und Kindern, die an CNGA3 verursachter Achromatopsie leiden, untersucht in einer randomisierten, Untersucher maskierten Studie mit Wartegruppendesign; Akronym: Colour Bridge,

https://doi.org/10.34657/33743.

Ruslan Nyshchuk, Joshua Klein, Immanuel P. Seitz, Tobias Peters, Matthias Mai, Taras Ardan, Saskia Drutovič, Božena Levinská Bohuslavová, Štefan Juhás, Jana Juhásová, Yesim Tütüncü, Yaroslav Nemesh, Lienne M. Reifferscheid, Kathryn Post DeMott, Jennifer J. Klein, Kerstin Nagel-Wolfrum, Nikolai Klymiuk, Ashley R. Winslow, Jan Motlik, Zdenka Ellederova, M. Dominik Fischer, Uwe Wolfrum, Subretinal injection in the USH1CR31∗ pig model leads to chorioretinal atrophy that limits evaluation of efficacy of an AAV-mediated gene therapy, Experimental Eye Research, Volume 271, 2026, 111151, ISSN 0014-4835, https://doi.org/10.1016/j.exer.2026.111151.

James Loughman, Gareth Lingham, Hakan Kaymak, Katrin Lorenz, Jan Roelof Polling, Anna Beck, Gonzalo Carracedo, Annegret H. Dahlmann-Noor, Philipp L. Müller, Ian Flitcroft, Ana Amorim-de-Sousa, Cristina Arroyo del Arroyo, Laura Batres, Carlos Carpena Torres, Christoph Deuter, Machteld Devenijn, Paulo R.B. Fernandes, Roxana Folga, Mariya Gosheva, Enrique Jimenez Gañan, Timea Katona, Caroline Klaver, Kübra Liman, Jose Manuel González-Meijome, Ann-Isabel Mattern, Marta Morales Ballús, Birte Neller, Cristina Pastrana Robles, Sofia C. Peixoto-de-Matos, Tobias Peters, Paloma Porras Ángel, María Serramito Blanco, Sara Silva-Leite, Julia Bodas Romero, MyopiaX-1 Safety and Efficacy of a Novel Approach to Slow Juvenile Myopia Progression: A Multicenter, Randomized, Controlled Trial, Ophthalmology Science, Volume 6, Issue 1, 2026, 100973, ISSN 2666-9145, https://doi.org/10.1016/j.xops.2025.100973.

Kortuem FC, Seitz I, Kaltenstadler S, Schumayer S, Sigdel B, Peters T, Rothermel A, Bucher V, Zrenner E, Bartz-Schmidt KU, Straßer T. Surgical Approach for the Implantation of a Ring Electrode into the Sulcus in a Phakic Non-human Primate. J Refract Surg. 2026 Feb;42(2):e151-e160. doi: 10.3928/1081597X-20251217-02. Epub 2026 Feb 1. PMID: 41665323.

Reichel FF, Fischer MD, Stingl K, Kuehlewein L, Seitz I, Peters T, Ziegler M, Wilhelm B, Kohl S, Weisschuh N, Martus P, Seeliger M, Muehlfriedel R, Paquet-Durand F, Tsang SH, Bartz-Schmidt KU, Ueffing M, Zrenner E, Biel M, Wissinger B, Michalakis S; RD-Cure Consortium. Safety and vision outcomes of subretinal gene supplementation therapy in PDE6A-associated retinitis pigmentosa: a non-randomised controlled trial. Br J Ophthalmol. 2026 Jan 22;110(2):173-179. doi: 10.1136/bjo-2024-326480. PMID: 40825661; PMCID: PMC12911619.

Vassili Valayannopoulos , Manohar Bance, Daniela S Carvalho, John H Greinwald Jr, Steven A Harvey, Akira Ishiyama, Evie C Landry, Hubert Löwenheim, Lawrence R Lustig, Manuel Manrique, Robert Nash, Rubén Polo, Cedric V Pritchett, Jay T Rubinstein, A Eliot Shearer, Ignacio Del Castillo, Jeffery J Anderson, C Eduardo Corrales, Tera M Quigley, William J Riggs, Peter Weber, Gary Wilson, Susan C Irvin, Hazem E Hassan, Yanping Chen, Rong Liu, Meghan C Drummond, Leah R Sabin, Bret J Musser, George D Yancopoulos, Christos A Kyratsous, Gary A Herman, Aris Baras, Jonathon P Whitton; CHORD Study Group, DB-OTO Gene Therapy for Inherited Deafness. N Engl J Med. 2025 Oct 12. DOI: 10.1056/NEJMoa2400521.

Frank G Holz, Yannick Le Mer, Mahiul MK Muqit, Lars-Olof Hattenbach, Andrea Cusumano, Salvatore Grisanti, Laurent Kodjikian, Marco Andrea Pileri, Frederic Matonti, Eric Souied, Boris V Stanzel, Peter Szurman, Michel Weber, Karl Ulrich Bartz-Schmidt, Nicole Eter, Marie Noelle Delyfer, Jean François Girmens, Koen A van Overdam, Armin Wolf, Ralf Hornig, Martina Corazzol, Frank Brodie, Lisa Olmos de Koo, Daniel Palanker, José-Alain Sahel, Subretinal Photovoltaic Implant to Restore Vision in Geographic Atrophy Due to AMD. N Engl J Med. doi: 10.1056/NEJMoa2501396.

Seitz, I. P., Wozar, F., Ochakovski, G. A., Reichel, F. F., Korte, S., Korbmacher, B., Wilhelm, B., Süsskind, D., Bartz-Schmidt, K. U., Fischer, M. D., Peters, T., & RD Cure Consortium (2025). Ocular Safety and Toxicology of Subretinal Gene Therapy With rAAV.hPDE6A in Nonhuman Primates. Translational vision science & technology, 14(1), 29. https://doi.org/10.1167/tvst.14.1.29.

Kiraly, P., Klein, J., Seitz, I. P., Reichel, F. F., Peters, T., Ardan, T., Juhasova, J., Juhás, S., Ellederova, Z., Nemesh, Y., Nyshchuk, R., Klymiuk, N., Nagel-Wolfrum, K., Winslow, A. R., Wolfrum, U., Motlik, J., & Fischer, M. D. (2025). Safety of Human USH1C Transgene Expression Following Subretinal Injection in Wild-Type Pigs. Investigative ophthalmology & visual science, 66(1), 48. https://doi.org/10.1167/iovs.66.1.48

Kahle N, Peters T, Braun A, Franklin J, Michalik C, Gekeler F, Wilhelm B; retina.net e. V.; TES-RP-Studiengruppe. Transkorneale Elektrostimulation bei Retinitis pigmentosa : Prüfplan einer multizentrischen, prospektiven, randomisierten, kontrollierten und doppelblinden Studie im Auftrag des Gemeinsamen Bundesausschusses (G-BA-Erprobungsrichtlinie) [Transcorneal electrostimulation in retinitis pigmentosa : Protocol of a multicentric prospective, randomized, controlled and double-masked trial on behalf of the Joint Federal Committee (G-BA pilot regulation)]. Ophthalmologe. 2021 May;118(5):512-516. German.